| 제목 |
Safety and efficacy of platelet-rich plasma for the treatment of chronic plantar fasciitis |
| 소속 |
St. Paul Hospital, The Catholic University of Korea, Department of Rehabilitation Medicine1, Incheon Hospital, Korea Workers’ Compensation and Welfare Service, Department of Rehabilitation Medicine2, National Traffic Injury Rehabilitation Hospital, Department of Rehabilitation Medicine3, The Catholic University of Korea Seoul St. Mary`s Hospital , Department of Rehabilitation Medicine4 |
| 저자 |
Jihye Park1*, Hyun Mi Oh2, Yujung Seo1, Young-Jin Ko1† |
Objectives
Plantar fasciitis (PF) is the most common cause of heel pain. The aim of this study was to evaluate the efficacy and safety of PRP for patients who were resistant to conservative management of PF.
Methods
Fifty-five chronic plantar fasciitis patients nonresponding to conservative management were included. 33 patients received ultrasound-guided 3ml autologous PRP injection and 22 patients received exercise education. All participants were encouraged to exercise for plantar fascia. Clinical outcome were evaluated by AOFAS hindfoot score, a visual analogue scale (VAS), 5-likert scale at 3 and 6months, and plantar fascia thickness using ultrasonography at 6months. The primary outcome was AOFAS hindfoot score at 3 months. Statistical analysis was done using SPSS version 24.0 software.
Results
In baseline analysis of the patients in the two groups, there was no difference in age, gender, body mass index, duration of symptoms, and location of symptoms between the two groups. But the AOFAS hindfoot score, VAS, 5-Likert scale and tendon thickness were significantly different, indicating that the symptoms of patients in PRP group were severe (Table 1).
In the primary outcome, the AOFAS hindfoot score in the PRP group increased from 70.56 ± 10.04 to 82.26 ± 8.58 with statistically significant improvement, while the score in the exercise group increased from 79.75 ± 8.8 to 82.25 ± 12.2 without statistical difference (Table 2).
In the secondary outcome, there were significant improvement in VAS and 5-Likert scale at 3 months in both groups. At 6 months, the AOFAS hindfoot score, VAS and 5-Likert scale were significantly improved in both groups compared with baseline. The thickness of the plantar fascia was significantly decreased from 0.61 ± 0.82 cm to 0.40 ± 0.21 cm in the PRP group over 6 months. However, the thickness of the exercise group decreased from 0.53 ± 0.09 to 0.51 ± 0.09 cm without significant difference. There was no serious adverse events in both groups.
Conclusion
We concluded that autologous PRP injection is safe and has a long term effect for improving pain and function in chronic plantar fasciitis. PRP injections can be recommended as a treatment option for patients with chronic recalcitrant plantar fasciitis.
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Table 1. Baseline values of PRP and control groups (based on the patients who visited at 3 months)
Table 2. Clinical results of PRP and control groups at 3 months.
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