Purpose
The purpose of study was to determine association between the occurrence of thromboembolism and the characteristics of cerebral infarction lesion (vascular territory location, etiology, size), rehabilitative evaluation outcomes when patients suspected of thromboembolism in rehabilitation setting after cerebral infarction.
Methods
This study was retrospective, cross-sectional study of admissions after cerebral infarction from January 2012 through April 2017. Patients who were suspected of thromboembolism and underwent evaluation were included in analyses. We divided patients into two groups: Patients who were normal or negative for evaluation (DVT(-) group) and patients who were diagnosed with DVT or PTE (DVT(+) group). For clinical variables with significant differences between two groups, logistic regression analysis was used to ascertain how the identified clinical variables were associated with the occurrence of thromboembolism.
Results
Total 27 patients (2.95%) were diagnosed with thromboembolism. Patients in DVT (+) group were more likely to have higher ratio of women, previous DVT history, MCA infarction, large arterial disease, mRS 5, abnormal speech and higher D-dimer than DVT (-) group. In multivariate logistic regression analysis, female gender, MCA infarction and mRS 5 were significantly associated with the occurrence of thromboembolism when patients were suspected of thromboembolism. In contrast, other rehabilitative evaluation outcomes, cerebral infarction etiology (TOAST classification) and infarct volume were not associated with the occurrence of thromboembolism.
Conclusion
Female gender, MCA infarction and mRS 5 could be the potential risk factors for thromboembolism in rehabilitation patients after cerebral infarction. For this work, further large-scale studies that compare thromboembolism group and non-thromboembolism group in cerebral infarction patients will be necessary.
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