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연제번호 : P-403 북마크
제목 Therapeutic Effect of Ultrasound Guided PDRN Injection into Subacromial Subdelto
소속 753 Artillery Battalion , Department of Rehabilitation Medicine1, Jang-Sa Battalion, Department of Rehabilitation Medicine2, Chun-in Medical Hospital, Department of Rehabilitation Medicine3
저자 Jae Hwal Rim1,1*, Jae Wook Lee1,2†, Dae Gil Kwon1,3
Background :
Rotator cuff tear (RCT) is a common cause of shoulder pain. RCT can be treated by medication, steroid injection. Recently, polydeoxyribonucleotide (PDRN) is used for tissue regeneration. PDRN can regenerate tissue by promoting DNA synthesis and stimulating A2 receptor. recently published studies reported about PDRN for tendon and ligament healing and no harmful side effects are reported. Subacromial subdeltoid (SASD) bursa is a main pain source of shoulder pain. Many sensory nerves innervates to SASD bursa, and main therapeutic target is focused on SASD bursa. The aim of our study is to evaluate the efficacy of ultrasound (US) guided PDRN injection into SASD bursa in patients with RCT.


Objective : To evaluate the short-term effect of polydeoxyribonucleotide (PDRN) in patients with rotator cuff tear (RCT).

Material and Methods : Thirty four patients (27 male, 7 female, mean age 52.3; range 32-62) with RCT were included. All patients were diagnosed by ultrasound (US) and treated with US guided PDRN injection into SASD bursa (Figure 1). Visual analogue scale (VAS), shoulder pain and disability index (SPADI), single assessment numeric evaluation (SANE) were measured pre-treatment, 1, and 3 weeks after treatment.

Results : One and 3 weeks after treatment, VAS, SPADI, SANE score were significantly improved compared with pretreatment (Table 1). There was no complications after PDRN injection.

Conclusion : PDRN injection into SASD bursa can be a useful treatment in patients with RCT.
Figure 1. Bursal side partial thickness rotator cuff tear was seen in ultrasound (A). Polydeoxyribonucleotide was injected on subacromial subdeloid bursa with ultrasound guidance (B).