| 제목 |
Relationship between the seasonal trend of viral infection and Bell’s palsy in South Korea |
| 소속 |
Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea, Department of Physical Medicine and Rehabilitation1, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea, Department of Pediatrics2 |
| 저자 |
Junmo Cho1*, Si Hyun Kang1†, Hyungsun Peo1, Kyung Mook Seo1, Don-Kyu Kim1, Du Hwan Kim1, Hyun Iee Shin1, Dae Yong Yi2 |
Background: Bell’s palsy is a unilateral facial paralysis caused by acute inflammation of the facial nerve. The cause of Bell’s palsy has not yet been clearly demonstrated, but several viruses are known to be related with Bell’s palsy. This study aimed to analyze the relationship between the seasonal trend of viral infection and the incidence of Bell’s palsy.
Methods: We reviewed the medical charts of patients with acute facial palsy who were referred for electroneuronography (ENoG) from March 2015 to February 2020. According to ENoG results, the patients were classified into two groups: one with axonal loss less than 70% (Group A) and another with 70% or more (Group B). The occurrence data of infection by viruses were collected from the Korea Centers for Disease Control and Prevention. A decomposition of additive time series analysis and a correlation analysis were used to analyze the correlation between the incidence of Bell’s palsy and occurrences of viral infections.
Results: Of the 187 patients with Bell’s palsy, the result of analyzing the correlation between the monthly incidence of Group A the monthly occurrences of viral infections showed that the outbreak patterns of influenza virus (r=0.806), coronavirus (r=0.766), norovirus (r=0.761), and respiratory syncytial virus (r=0.758) were statistically similar (Table 1). In Group B, no viral infection was identified that displayed similar statistically significant pattern.
Conclusion: We found that the monthly incidence of Group A Bell’s palsy showed statistically similar pattern with monthly occurrence of several viruses. To clarify the relationship of viral infection and the incidence of Bell’s palsy, a long-term study with a large number of patients will be required, and serological studies for the suspected viruses should be considered. |
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Table 1. Correlation analysis between the monthly incidence of Bell’s palsy and the monthly occurrences of viral infections.
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