Introduction
Because hip osteoarthritis (OA) is rare in Asians, the characteristics of individuals with hip OA and their association with osteoporosis (OP) are unknown. This study aimed to investigate the association of hip and lumbar spine (LS) bone mineral density (BMD) with radiographic hip osteoarthritis in the general population.
Method
Cross-sectional data from 5667 community-dwelling participants (2426 men and 3241 women) aged ≥ 50 years in the Korea National Health and Nutrition Examination Surveys were analyzed. BMDs for the femoral neck (FN), total hip (TH), and LS were measured using dual-energy X-ray absorptiometry. Radiographic changes relating to hip OA were assessed using the Kellgren-Lawrence (KL) grading scale. The mean BMD, according to the presence of radiographic hip OA (KL grade ≥ 2) were analyzed using the general linear models adjusted for anthropometric and biochemical confounders.
Results
Individuals with hip OA had a higher proportion of males, diabetes mellitus and hip pain (P = 0.049, P = 0.038, and P = 0.037, respectively) than the controls without hip OA. The individuals with hip OA showed significantly lower physical activity level than the control group (P = 0.016). The proportion of osteopenia and osteoporosis were lower in participants with hip OA than controls (P = 0.012). Adjusted FN and LS BMDs were significantly higher in participants with hip OA (P = 0.009 and P = 0.002, respectively). However, adjusted TH BMD was similar between participants with hip OA and controls (P = 0.064).
Discussion
There is an inverse relationship between hip OA and OP measured in FN and LS. The effects of confounders on BMD may be greater in TH than in FN and LS. |
