| 제목 |
Validity of the TIMP-SI test to Assess Motor Development in Preterm Infants |
| 소속 |
Ulsan University Hospital, Department of Physical Medicine and Rehabilitation1, Asan Medical Center, Department of Rehabilitation Medicine2 |
| 저자 |
Eun Jae Ko1*, In Young Sung2†, Eun Jung Choi2, Nayoung Heo2, Nam Hyun Lee2 |
Introduction: Preterm infants are high risk group for developmental delay. The Test of Infant Motor Performance Screening Items test (TIMPSI) is a shorter screening version of the Test of Infant Motor Performance. The aim of this study was to assess the relationship between TIMPSI and the Alberta Infant Motor Scale (AIMS) in preterm infants.
Method: Total 139 infants were scheduled to receive TIMPSI at 34-40 weeks postmenstrual age (PMA), 1 month, and 3 months corrected age (CA) and AIMS at 4, 8, 12-months CA. The association between the z-score on the TIMPSI and AIMS percentile ranks (PR) was analyzed. The age at which the best correlation occurred between TIMPSI and AIMS was selected for analysis of sensitivity and specificity for predicting AIMS performance below the 10th PR at 4, 8, and 12 months.
Results: Baseline characteristics of the infants are shown in Table 1. TIMPSI at 34-40 weeks PMA, 1 month, and 3 months CA showed correlation with AIMS at 4 and 8 months CA (p<0.05), except TIMPSI at 1 month CA and AIMS at 4 months CA (Table 2). However, TIMPSI at all periods were not related with AIMS at 12 months CA. The best TIMPSI to maximize specificity and correctly identify 86% of the infants above versus below the 10th PR at 4 months was a TIMPSI at 34-40 weeks PMA with a cut-off point of 2 SD below the mean (Table 3). The same cut-off point correctly identified 74% of the infants at 8 months. However, the best TIMPSI to maximize specificity and correctly identify 84% of the infants above versus below the 10th PR at 12 months was a TIMPSI at 3 months CA with a cut-off point of 2 SD below the mean.
Conclusion: TIMPSI scores significantly predict AIMS PR 4 to 8 months later. TIMPSI at 34-40 weeks PMA has the greatest validity for predicting motor performance on the AIMS at 4 and 8 months, whereas TIMPSI at 3 months CA has the greatest validity for predicting motor performance on the AIMS at 12 months. |
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Table 1. Clinical and demographic characteristics (total n=139)
Table 2. Pearson’s correlation between TIMPSI and AIMS test results at various ages
Table 3. Summary of diagnostic efficiency of TIMPSI in predicting performance on AIMS at 4, 8, and 12 months
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