제목 | The Relationship between Body Muscle Mass and Respiratory Muscle Strength after Lobectomy Patients | ||
---|---|---|---|
소속 | Pusan National University Hospital, Department of Rehabilitation Medicine1, East Gimhae Hospital, Department of Rehabilitation Medicine2, Pusan National University Hospital, Biomedical Research Institute3, Pusan National University Hospital, Department of Thoracic and Cardiovascular Surgery4 | ||
저자 | Ra Yu Yun1*, Myung Jun Shin1, Byeong-Ju Lee1, Sang Hun Kim1, Je-Sang Lee2†, Bo-Hyeon Kim3, Jong-Hwan Park3, Jeong Su Cho4, Hyo Yeong Ahn4 | ||
Introduction
The purpose of this study was to compare the body composition, cardiopulmonary function, pulmonary function and respiratory muscle strength of lung cancer patients of pre and post lobectomy, and showed following result in relation of removed lung volume with muscle mass, lung function and respiratory muscle strength. Methods The present study was approved by the Institutional Review Board (IRB) at B Hospital. Recruitment notices were posted at the thoracic surgery and rehabilitation medicine clinic at B Hospital to recruit patients scheduled to undergo video-thoracoscopic lobectomy for lung cancer. Before lobectomy, the patients underwent computed tomography (CT), cardiopulmonary exercise testing (CPET), pulmonary function test, Inbody dual energy X-ray absorptiometry (DEXA), whole body DEXA, and grip strength measurements. These tests were repeated four weeks after surgery. One week after surgery, all tests except CT, CPET, and whole body DEXA were performed. All evaluations were performed by a single skilled physician. Thirteen patients with lung cancer were enrolled in this study. Their mean age was 65±6.84 years, with 9 men and 4 women. Result The maximum oxygen uptake per body weight was significantly decreased from 26.34±6.98 ml/kg/min to 23.13±4.66 ml/kg/min after 4 weeks(p<.01). Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) showed significant differences between pre-operation, 1 week and 4 weeks of operation. Maximal inspiratory pressure (MIP) was significantly different between the periods(p<.05). Peak expiratory flow (PEF) was also significantly different between the periods(p<.001). The correlation between muscle mass and MIP, muscle mass and PEF is shown in The correlation between muscle mass, respiratory muscle strength, pulmonary function according to pre and post-operative lung volume is shown in
|